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Minor Bodies in the Outer Solar System
  • Language: en
  • Pages: 192

Minor Bodies in the Outer Solar System

This volume tries to summarize the status of observational knowledge of the Kuiper Belt. Its recent discovery has revitalized the astromomical study of the Solar System and is beginning to open new and unexpected windows on the physics of planetesimal accretion. With more and better observational data being obtained at the technological limit of current facilities, a new perception of the relationships that exist among the various classes of small Solar System bodies has emerged. The new observations have also motivated a number of fascinating theoretical studies in Solar System dynamics.

The Extracellular Matrix: an Overview
  • Language: en
  • Pages: 426

The Extracellular Matrix: an Overview

Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.

Testing of Metals
  • Language: en
  • Pages: 202

Testing of Metals

This book contains information on equivalent national and international standard BIS, ASTM, BS, DIN, ISO and JIS - on testing of metals, hardness conversion tables, macroetchants and microetchants for metals. Besides this, a directory of select standards organizations, technical associations, and testing equipment manufacturers are also included.

Sexual Reproduction in Animals and Plants
  • Language: en
  • Pages: 480

Sexual Reproduction in Animals and Plants

  • Type: Book
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  • Published: 2014-02-07
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  • Publisher: Springer

This book contains the proceedings of the International Symposium on the Mechanisms of Sexual Reproduction in Animals and Plants, where many plant and animal reproductive biologists gathered to discuss their recent progress in investigating the shared mechanisms and factors involved in sexual reproduction. This now is the first book that reviews recent progress in almost all fields of plant and animal fertilization. It was recently reported that the self-sterile mechanism of a hermaphroditic marine invertebrate (ascidian) is very similar to the self-incompatibility system in flowering plants. It was also found that a male factor expressed in the sperm cells of flowering plants is involved in gamete fusion not only of plants but also of animals and parasites. These discoveries have led to the consideration that the core mechanisms or factors involved in sexual reproduction may be shared by animals, plants and unicellular organisms. This valuable book is highly useful for reproductive biologists as well as for biological scientists outside this field in understanding the current progress of reproductive biology.

An Outlander Collection
  • Language: en
  • Pages: 2912

An Outlander Collection

  • Type: Book
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  • Published: 2016-12-08
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  • Publisher: Random House

Read the first three books in the million-copy bestselling Outlander series that inspired the TV show. What if your future was the past? Book 1: Outlander 1946, and Claire Randall goes to the Scottish Highlands with her husband Frank. It’s a second honeymoon, a chance to learn how war has changed them and to re-establish their loving marriage. But one afternoon, Claire walks through a circle of standing stones and vanishes into 1743, where the first person she meets is a British army officer - her husband’s six-times great-grandfather. Unfortunately, Black Jack Randall is not the man his descendant is, and while trying to escape him, Claire falls into the hands of a gang of Scottish outl...

Mechanobiology
  • Language: en
  • Pages: 432

Mechanobiology

An emerging field at the interface of biology and engineering, mechanobiology explores the mechanisms by which cells sense and respond to mechanical signals—and holds great promise in one day unravelling the mysteries of cellular and extracellular matrix mechanics to cure a broad range of diseases. Mechanobiology: Exploitation for Medical Benefit presents a comprehensive overview of principles of mechanobiology, highlighting the extent to which biological tissues are exposed to the mechanical environment, demonstrating the importance of the mechanical environment in living systems, and critically reviewing the latest experimental procedures in this emerging field. Featuring contributions f...

Intrinsically Motivated Learning in Natural and Artificial Systems
  • Language: en
  • Pages: 458

Intrinsically Motivated Learning in Natural and Artificial Systems

It has become clear to researchers in robotics and adaptive behaviour that current approaches are yielding systems with limited autonomy and capacity for self-improvement. To learn autonomously and in a cumulative fashion is one of the hallmarks of intelligence, and we know that higher mammals engage in exploratory activities that are not directed to pursue goals of immediate relevance for survival and reproduction but are instead driven by intrinsic motivations such as curiosity, interest in novel stimuli or surprising events, and interest in learning new behaviours. The adaptive value of such intrinsically motivated activities lies in the fact that they allow the cumulative acquisition of ...

Non-coding RNAs in Colorectal Cancer
  • Language: en
  • Pages: 252

Non-coding RNAs in Colorectal Cancer

  • Type: Book
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  • Published: 2016-08-29
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  • Publisher: Springer

This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles played by non-coding RNAs in molecular hallmarks of colorectal cancer. This work further provides the comprehensive overview and novel insights into using of non-coding RNAs as colorectal cancer biomarkers enabling early detection of the disease, prognostic stratification of the patients and prediction of therapeutic response. The reader is introduced to the overview of modern non-coding RNAs-based therapeutic strategies, and summary of their preclinical testing performed in colorectal cancer. The work is written for researchers who want to explore current state of the knowledge in this interesting field of molecular oncology.

Cell Membrane Nanodomains
  • Language: en
  • Pages: 510

Cell Membrane Nanodomains

  • Type: Book
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  • Published: 2014-10-27
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  • Publisher: CRC Press

Cell Membrane Nanodomains: From Biochemistry to Nanoscopy describes recent advances in our understanding of membrane organization, with a particular focus on the cutting-edge imaging techniques that are making these new discoveries possible. With contributions from pioneers in the field, the book explores areas where the application of these novel techniques reveals new concepts in biology. It assembles a collection of works where the integration of membrane biology and microscopy emphasizes the interdisciplinary nature of this exciting field. Beginning with a broad description of membrane organization, including seminal work on lipid partitioning in model systems and the roles of proteins i...

Boiler (Efficiency) Regulations 1993
  • Language: en
  • Pages: 20